We help laboratories and clinical teams preserve, handle and deliver high-value biological products. Our development approach focuses on three priorities.
01
Protect the product
Design for closed handling, with contamination risk and sample integrity in mind.
02
Preserve the dose
Address sample loss and recovery when working with small, high-value volumes.
03
Simplify the workflow
Connect steps and reduce unnecessary transfers between devices.
DESIGN & DEVELOPMENT
From clinical needs to device design.
We translate handling challenges into device concepts, working with our clinical and engineering partners to develop practical solutions for advanced therapies.
Development supported by specialist facilities
Through our partnership with Leartiker, we have access to a 65 m² ISO Class 7 cleanroom with thermoplastic and liquid silicone rubber (LSR) injection moulding capabilities, supported by Leartiker’s ISO 13485-certified quality management system.
Clinical insightEngineering designManufacturing in mind
CRYOKEEP
In development · Preclinical evaluation underway.
From cryopreservation to patient delivery. All in one closed system.
CryoKeep is a single-use device designed to integrate the cryopreservation, transport and administration of human cells for advanced therapies.
Designed to receive the cellular product in volumes from 1 to 5 mL.
02
Seal
Designed to close the system after loading.
03
Cryopreserve
Designed for cryogenic preservation of the cellular product.
04
Dispense
Designed for delivery from the same device.
The device is also designed to keep the cellular product in the same system during transport.
WHY CRYOKEEP
Every small volume matters
Designed to protect valuable cellular products and simplify their journey to the patient.
CryoKeep prototype · Original photograph
A closed pathway
Designed to minimise contamination risk by integrating cryopreservation, transport and administration within one closed system.
Focus on dose recovery
Designed to minimise sample loss and support volume recovery during administration.
Continuity through the workflow
Keeping the cellular product in the same device is intended to simplify handling and support traceability.
Cell viability in mind
Preserving cell viability through handling and administration is a core design objective.
DEVELOPMENT PROGRESS
Moving towards the first clinical batch.
Last updated:
Completed
Prototypes developed
CryoKeep prototypes have been developed.
In progress
Preclinical evaluation
Preclinical evaluation is underway.
In progress
Final design
We are finalising the design in preparation for manufacturing the first clinical batch.
OUR DEVELOPMENT VISIONHigh-value biological products
PreparePreserveDeliver
Connected by design.
OUR VISION
Engineering the journey of advanced therapies.
At LTK CRYOsolutions, we are developing complementary tools for cell therapy handling, with a shared focus on connecting preservation, handling and delivery.
FIRST PRODUCT IN DEVELOPMENT
CryoKeep
A single device designed to connect cryopreservation, transport and administration.
PLANNED EXPANSION
Storage & handling
Complementary containers, boxes and racks, alongside future device variants.
LONGER-TERM DIRECTIONS
Connected workflows
Potential solutions for filling, aliquoting and freezing or thawing operations.
EXPLORING COMPLEMENTARY SOLUTIONS
Thinking beyond the device.
Packaging, storage and handling concepts that build on the CryoKeep workflow.
Edilberto combines a PhD in Biomedicine with an MBA and experience in medical device development, technology transfer and business development.
His background spans gene delivery research, microfluidics and the development of biomedical technologies in academic and industry settings. At LTK Cryosolutions, he leads the company’s development, working with Leartiker and Clínica Universidad de Navarra to advance CryoKeep.
SCIENTIFIC & MEDICAL ADVISORS
Expertise connecting science and clinical practice.
Scientific Advisor
Dr. Enrique J. Andreu Oltra
Clínica Universidad de Navarra
Technical and Quality Assurance Director of the Cell Therapy GMP Laboratory at Clínica Universidad de Navarra. His expertise spans stem cell biology, advanced therapies and the manufacture of therapeutic cell products under EU GMP standards.
Director of Cell Therapy and Co-director of Hematology and Hemotherapy at Clínica Universidad de Navarra. A clinician and translational researcher, he has led more than 30 clinical trials as principal investigator, connecting cell therapy research with clinical practice.
